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The latter is especially critical for enhancing long-term patient adherence, a key determinant of therapeutic durability
Profiling the gasdermin D-targeting proteases also illuminated why variants evolved on GD_Sh were able to pass PACE selection but failed to cleave longer gasdermin D substrates in vitro
In parallel, health systems should consider commissioning large RWS to understand the full benefits of GLP-1s in routine use including outcomes in the many patients currently using these drugs out-of-pocket
Key Takeaways From This Blog: GLP-1 updates highlight growing use of these medications and their impact on employer health plans
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