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However, self-medication or excessive treatment may increase the risk of the side effects of glutathione injection, including allergic reactions, digestive discomfort, and skin sensitivity

Caspase inhibitors, overexpression of the anti-apoptotic Bcl-2, p53 inhibitors, and the STAT1 inhibitor epigallocatechin gallate, which can reverse Bcl-2 family equilibrium toward antiapoptosis, have been proposed as protective measures for hair cells against apoptosis caused by cisplatin (Wu et al

The primary concern lies in its bioavailability, or the extent to which glutathione is absorbed and utilised by the body when taken orally

This study was approved by the institutional review board (IRB) of the Taipei VGH, which waived the requirement for individual written patient consent (IRB approval No