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Abstracts Cuglievan B , Jen WY, Short NJ, Bataller A, DiNardo CD, Loghavi S, Daver N, MD, Farhat A, Hajjar GE, McCall D, Gibson A, Garcia M, Nunez C, Roth M, Kadia TM, Bazinet A, Jabbour E, Montalban-Bravo G, Ravandi F, Garcia-Manero G, Andreeff M , Kantarjian HM, Issa GC
READ: Are You Pooping Gold
To increase the stability of GLP-1R, the fusion protein rubredoxin was inserted into intracellular loop 2 (ICL2) of GLP-1R between positions 257 to 262 and 11 mutations were introduced
Second-Messenger Cascades:The elevation of intracellular calcium and modulation of cAMP leads to downstream phosphorylation eventsand transcriptional responses in somatotropic cells of the anterior pituitary
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