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Vitamin B12 has a good safety profile, but some important considerations include rare hypersensitivity reactions (including anaphylaxis) with injections, potential hypokalaemia during early treatment of severe deficiency, and possible cutaneous reactions

Notably, while neuronal elements (axons, neurons, dendrites, and synapses) are also damaged to a significant extent (Mck et al., 2021), demyelination is a constant finding in both white and gray matter regions pointing to the myelinating unit (the myelin sheath and oligodendrocyte) as a key target in this disease

Remember, B12 helps build and maintain the myelin sheath around your nerves, and without enough B12, it begins to recede