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Therapie 2020;75:641-7.ArticlePubMed 12
freezing causes ice crystal formation that irreversibly shears peptide chains
Body Weight Reduction Body weight, from a mean baseline of 95.2 kg, was reduced by 4.6 kg and 2.3 kg in semaglutide 0.5 mg and dulaglutide 0.75 mg, respectively, while in semaglutide 1.0 mg and dulaglutide 1.5 mg, it was reduced by 6.5 kg and 3.0 kg, respectively
Nat Commun 2012
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