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What is the underlying issue

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DOI: 10.1161/HYP.0000000000000065 Wimalasena K (2011): Vesicular Monoamine Transporters: Structure-Function, Pharmacology, and Medicinal Chemistry

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Originally developed to treat type 2 diabetes, it has shown promise in helping individuals lose weight

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performed in vitro experiments using hippocampal organotypic brain slice cultures and demonstrated that the FGF-21 analog LY2405319 upregulates the mRNA expression levels of PPAR, ApoE, and ABCA1, while also reducing the number and size of A plaques [100]

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