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Modern liver-specific IGF-1 knockout studies have shown that local IGF-1 contributes substantially to tissue IGF1R activation, separate from the endocrine pool
However, a review of recent studies indicates that this is soon to change as more clinicians become aware of the unique advantages of nasal delivery of peptides and other therapeutics
Such molecules often contain several proteinprotein interaction domains
Now, a new translational study by the same research team reveals that targeting senescent cell burden could be an effective strategy for managing periodontal disease and promoting oral health
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