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A 2025 human pilot study reported no adverse cardiac, hepatic, or renal effects at IV doses of 10-20mg

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Cyanocobalamin (Vitamin B12) Injection Cyanocobalamin (Vitamin B12) Injection (30 mL Vial) Cyanocobalamin (Vitamin B12) Injection (10 mL Vial) commercial product Product Overview Cyanocobalamin (vitamin B12) injection is a sterile, prescription-only parenteral formulation of a water-soluble cobalamin analogue that serves as the principal therapeutic option when oral absorption of the vitamin is impaired or when rapid repletion is clinically required

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