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Retatrutide does not cure obesity

27 Importantly, GLP-1 action is short-lived, with a half-life of just 12 minutes in the bloodstream under normal physiological conditions, after which it is broken down by the enzyme dipeptidyl peptidase IV (DPP-4), resulting in a loss of its biological activity

Finally , for reference, see this Scientific Context: Study on L-Carnitine and Exercise.

Las aplicaciones una vez por semana con agentes como semaglutida o dulaglutida pueden ser la opcin preferida para muchos pacientes debido al efecto duradero y la mejor tolerabilidad en algunos pacientes