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Start metformin at a low dose (500 mg once or twice daily) and titrate slowly at intervals set by your prescriber, commonly about every 4 weeks to minimize GI upset

Data from the International Diabetes Federation Diabetes Atlas reveals a global uptrend in the prevalence of T2D, projected to reach 783 million among individuals aged 20 to 79 by 2045 [2]

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1 Interestingly, HGH deficiency in adults predisposes insulin resistance