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481,482 Under oxidative stress conditions, integrins can form disulfide bonds (e.g., Cys560-Cys583 and Cys523-Cys544 in the 3 subunit) that lock them in an inactive, bent conformation, preventing them from engaging with the ECM
58 In addition, Genome-wide CRISPR/Cas9-mediated screen uncovered that cytochrome P450 oxidoreductase promoted ferroptosis across a wide range of lineages and cell-states by peroxidation of membrane polyunsaturated phospholipids
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