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Additionally, improved glycemic control with GLP-1 RAs in T2DM patients may reduce glycosuria, a process known as glycemic buffering, which reduces caloric loss through urine and offsets part of the energy deficit induced by treatment [43,44,45]
doi: 10.1038/s41380-022-01792-4 68
Current research presents a complex picture that requires careful interpretation, as studies have yielded mixed results depending on the specific agent studied, patient population, duration of treatment, and methodology employed
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