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The genomic landscape of malignant peripheral nerve sheath tumors: diverse drivers of Ras pathway activation
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Originally developed as an analogue of Melanotan II, PT-141 functions as a melanocortin receptor agonist and has been extensively studied for its interaction with melanocortin receptors, particularly MC3R and MC4R, which are believed to play important roles in central nervous system signalling, appetite regulation, energy homeostasis and reproductive physiology
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