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CONCLUSIONES Los frmacos pertenecientes a la familia de los GLP1-RA surgieron luego del entendimiento del efecto incretina que tena el GLP-1, adems de participar en la regulacin del apetito, en el metabolismo de los carbohidratos y en funciones cardiovasculares

Here, we show that substitution of phenylalanine for leucine at position 973 in the IR decreases IRS-1/PI3K/Akt/mTORC1 signaling, upregulates Shc/Gab1/MAPK signaling and cell cyclerelated pathways, and decreases ligand-stimulated receptor internalization in vitro

CAS Registry Number: 910463-68-2