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Another example of precursor use involves L-2-oxothiazofidine-4-carboxylate, which is converted to S-carboxyl-L-cysteine and undergoes spontaneous decarboxy-lation to liberate L-Cysteine, thereby supporting GSH synthesis

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Compared with ADCs, PDCs exhibit better tumor penetration because of their small molecular weight, lower systemic exposure (owing to rapid clearance from the body), lower risk of immunogenicity and liver damage, and easier and cheaper production methods

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