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HOW PRE-WORKOUT WORKS: Caffeine: Boosts energy and alertness Citrulline: Improves blood flow and muscle pump Beta-alanine: Enhances endurance Other stimulants: Increased focus and strength Pre-workout is best for people who want a powerful boost before training

IP3 facilitates calcium ion (Ca2+) release from the endoplasmic reticulum, while DAG activates protein kinase C (PKC)

That large meal is sitting in your stomach much longer than usual, fermenting, producing gas, and eventually hitting your intestines in a wave that your altered motility cannot handle smoothly

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