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The SmPC recommends gradual dose titration to minimise these adverse effects, starting with 0.25 mg once weekly and increasing every 4 weeks to reach the maintenance dose of 2.4 mg
Neuroscience 57:473482 Kato T, Shinoda J, Oka N, Miwa K, Nakayama N, Yano H et al (2008) Analysis of 11 C-methionine uptake in low-grade gliomas and correlation with proliferative activity
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