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In one major trial, weight loss on semaglutide leveled off around week 60, then stayed fairly stable after that
Week 5: Add MOTS-C (250mcg/day, ramp to 500mcg/day over 2 weeks) + NAD+ (250500mg/day NMN or NR)
Use stool softeners or fiber supplements (consult your doctor before use)
Many people with detectable anti-tirzepatide antibodies have no injection site reactions at all, and the antibodies do not appear to reduce the medication effectiveness in most cases
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