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Although the uptake ratios of tumor per kidney in most of the 18 F-labeled exendin-4 probes were reported as less than 1.0 18 , some modifications such as [ 18 F]FPenM-[Cys 40 ]exendin-4 and [ 18 F]FNEM-[Cys 40 ]exendin-4 successfully demonstrated improved uptake ratios of tumor per kidney that were comparable to our PEGylated probe 31,32
Khavinsons research suggested that epitalon could activate telomerase, potentially slowing cellular aging
The mechanism is central, not peripheral
964 Vos, R
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