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A recent study found that administering DADS at doses of either 40 or 80 mg/kg produced therapeutic effects comparable to those of imipramine, a prescription antidepressant at a dose of 10 mg/kg, in treating mice with depression-like behaviors induced by LPS (160)

These changes can create temporary disruption before improvement emerges

Further, cytoplasmic PRDX1 modulates apoptosis via the associations with a series of ROS-dependent effectors [41, 42]

Xenobiotics containing a carboxyl group (COOH) are widely used as drugs (for example simvastatin, valproic acid, or acetylsalicylic acid), herbicides, insecticides, and food preservatives