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PGI2 (prostacyclin) is a potent vasodilator and inhibitor of

reported for the first time that liraglutide exhibited significant anti-proliferation and pro-apoptotic effects on gemcitabine-resistant human pancreatic cancer cells resistant to a variety of drugs, by regulating the NF-B signaling pathway and downstream ATP-binding cassette subfamily G member 2 (ABCG2) (213, 214)