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The researchers hypothesized the potential action of the AHK-Cu copper peptide complexes on collagen formation by attempting to isolate the quantity of collagen type I produced by fibroblasts in a cell culture
The Hostynek and Maibach group at UCSF measured exactly this in 2011: human skin permeation of GHK-Cu as a function of skin layer, with the result that the peptide accumulates in the upper stratum corneum but does not pass through to viable epidermis or dermis in any meaningful quantity 4
Brandenberger, G., et al
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