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World J Gastroenterol 2012
The target (then the reality) A 2025 joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society gives GLP-1 users a clear protein frame: Best target: about 1.5 g protein per kg of lean body mass per day If you dont know lean mass: 80120 g protein per day for most adults During active weight loss: about 1.21.6 g per kg body weight (use adjusted body weight at higher BMIs so total weight does not overstate need) Floor you should not live under: roughly 0.40.5 g/kg/day Protein alone is not enough the same advisory pairs this with resistance training at least three times per week (plus weekly aerobic activity) practical teaching aid for protein-first priority not a trial diet protocol
Another risk factor is a low-fiber diet, which can lead to constipation and straining that creates additional pressure
and Chang et al
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