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It had limited food-supplement GRAS history in some jurisdictions but Australia's TGA placed it on Schedule 4 (prescription) in 2020
Intrinsic factor, a protein that shuttles B12 through the absorption process, becomes saturated after a meal containing an above-average amount of B12 and about 4 to 6 hours are required before it can efficiently absorb another dose (IOM, 1998)
Patients with active cancer should discuss peptide therapy carefully with their oncologist
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