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Research indicates that reduced glutathione supplementation supports cognitive performance through multiple pathways beyond simple antioxidant protection
The variability is the practical issue
Thermo Fisher Scientific, Waltham, MA, USA) and -MEM (Thermo Fisher Scientific), respectively, supplemented with 10% fetal bovine serum (FBS) and 1% penicillin-streptomycin (P/S) at 37 C and 5% CO
In addition, some proteins can stimulate tumor cells to switch from oxidative phosphorylation (OXPHOS) to glycolysis, in turn leading to lower levels of GSH, which suppress the activity of GPX4 and boost the accumulation of lipids, thus resulting in ferroptosis [21,22,23,24]
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