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Leaky gut, dysbiosis (microbial imbalances), and small intestinal bacterial overgrowth (SIBO) can contribute to MCAS by increasing inflammation and allowing undigested food particles to trigger immune responses

Presented for research literature review only Shaikh AK (2025)

doi: 10.4239/wjd.v14.i5.481 8 CarmelliniP.CuomoA.RescalliM

NAION represents an equally devastating complication, causing sudden and irreversible vision loss when blood flow to the optic nerve stops, requiring patients to seek medical attention immediately