Pepin offers a few suggestions for improving sleep hygiene, whether youre taking semaglutide or not: Keep a consistent bedtime and wake time, even on the weekends
If you see sleep and energy improvements but IGF-1 has not moved, the dose may need adjustment
lactis, Lacticaseibacillus casei, Lactococcus lactis, Ligilactobacillus salivarius, Lacticaseibacillus paracasei, Limosilactobacillus fermentum, Lactobacillus helveticus, Lactobacillus gasseri, Lactobacillus bulgaricus, Limosi lactobacillus reuteri, Streptococcus thermophilus, Bifidobacterium longum, Bifidobacterium breve, Bifidobacterium bifidum, Lactobacillus acidophilus, Processed Starch Products), Hydrolyzed Elastin, Hyaluronic Acid *Contains Milk, Soybean, Tomato Ingredients subject to change at manufacturer's discretion
Ipamorelin dosing at 200-300 mcg comes from Bowers' dose-response work in the 1990s and subsequent phase-I/II trials showing reliable GH pulses at that range