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EMA Decision P/0336/2024 Paediatric Investigation Plan for retatrutide
model 2: adjusted by age (as continuous variable), sex (male or female), body mass index (as continuous variable), type II diabetes (yes or no), pulmonary diseases (yes or no), psychiatric diseases (yes or no), hypertension (yes or no) and rheumatic disease (yes or no)
Alcohol promotes the production of ROS in various ways: 1) stimulating cytochrome P450s activity, 2) altering certain metal concentrations, 3) decreasing the antioxidants level, 4) directing the conversion of xanthine dehydrogenase (XDO) into xanthine oxidase (XO)
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