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281 Importantly, while acute or overwhelming endoplasmic reticulum stress can induce cell death, chronic UPR activation favors drug tolerance and persistence, positioning endoplasmic reticulum stress adaptation as a systems-level resistance mechanism complementary to oncogenic signaling network adaptation
They narrowed it down to 36 total studies
10.2174/13816128113199990421 100 SeiwerthS.RucmanR.TurkovicB.SeverM.KlicekR.RadicB.et al (2018)
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