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What the Evidence Shows The clinical trial data for GLP-1 medications is among the strongest ever produced for a non-surgical weight loss intervention: Ozempic (semaglutide 12mg): Mean weight loss of approximately 1012% of body weight over 4068 weeks in SUSTAIN trials Wegovy (semaglutide 2.4mg): Mean weight loss of 1517% of body weight over 68 weeks in STEP trials Mounjaro (tirzepatide 15mg): Mean weight loss of 2022% of body weight over 72 weeks in SURMOUNT trials For context, older weight loss medications typically produced 58% weight loss
5 Briefly, the conversion of dietary precursors into TMA involves four enzymatic pathways, including the choline-utilizing TMA lyase system (CutC/D), the carnitine Rieske-type oxygenase/reductase system (CntA/B), betaine reductase, and TMAO reductase
Before SoWell, patients were being recommended 15 or more individual supplements with no single product meeting the standard for GLP-1 users
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