This is not merely a speculative problem, because both a severely atypical melanocytoma and a melanocytoma-like classical melanoma will likely spread to the regional nodes, but only the latter will be candidates to sentinel node biopsy and, possibly, to an adjuvant therapy with BRAF -inhibitors or with immune checkpoint inhibitors (79, 80)
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With GLP-1 therapy, especially when combined with proper resistance training and protein intake , the ratio shifts dramatically toward fat loss while preserving lean mass