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Although one mole of ATP is used by hexokinase and an additional mole of ATP by phosphofructokinase, the net gain is 2 moles of ATP per mole of glucose, because a total of 4 moles of ATP is formed per mole of glucose by phosphoglycerate kinase and pyruvate kinase
And of course, [it can result in] the stuff you saw with cardiovascular disease
M.FranklinM.OlerE.WilsonA.et al (2024)
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