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When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives

For the entire group, the median vitamin B12 level before treatment was 328 (range, 244429) pmol/l, and 973 (range, 4761476) pmol/l after treatment

Same day, different injection sites is the standard pattern

People already doing scalp microneedling who want a well-reasoned topical to pair with it