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By statistical analysis of the proportion of cells in each sample, we found that only dopaminergic neurons were significantly decreased in the SN pars compacta in PD patients, and that other six groups of cells were not changed obviously (Fig

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To test the involvement of NRF2, we bred the Gclc f/f mouse strain with the Nrf2 f/f mouse strain 57,58 and induced a liver-specific double deletion with the AAV-TBG-Cre virus (hereafter referred to as L-DKO) (Fig

The approval addresses the growing need for treatments in the face of increasing obesity rates in the U.S