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In contrast, the high fat diet reduced SCFA production and induced gut dysbiosis
The accumulation of senescent cells and the production of the SASP further exacerbate the inflammatory state and oxidative stress, accelerating the aging process
Dysregulation is a hallmark of both chronic wounds and photoaged skin models
These types of therapies therefore generally require high doses and long treatment durations, which increase the risk of undesirable side effects
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