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However, this same mechanismfood sitting longer in the stomachis also the root cause of many common gastrointestinal side effects like nausea, vomiting, bloating, and reflux, especially if large meals or slow-digesting foods (like high-fat items) are consumed
Did not show efficacy for postoperative ileus
GLP-1RA: receptor agonists for hormone glucagon like peptide-1
Clinical trials have demonstrated varying degrees of weight loss depending on the specific agent and dosage: semaglutide 2.4mg (Wegovy) produces approximately 15% weight loss at 68 weeks, liraglutide 3mg (Saxenda) typically achieves 5-8% weight loss, while tirzepatide has shown up to 20% weight reduction in obesity trials
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