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Whilst these procedures typically produce substantial initial weight loss, weight regain is a recognised clinical challenge that affects a significant proportion of patients in the years following surgery

What to Expect in Months 7-11 Essentially no side effects: Appetite suppression continues (desired effect), but GI symptoms gone Weight loss velocity slows: From 0.8kg/week (months 3-6) to 0.3-0.5kg/week Plateau around week 40-48: Weight stabilizes, no longer losing despite continued medication Total weight loss: Average 20-24% from baseline (matching or exceeding surgical outcomes) Focus shifts to maintenance: Accepting current weight, preventing regain Plateau frustration: Not a side effect but an emotional challenge 2 Final Strategies for Months 7-11 20

Both inflammation and remodeling influence nitric oxide output in children with refractory asthma

Because we start low and increase your dose gradually, side effects are usually mild and ease within the first few weeks