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46 In keeping with this, transgenic mice overexpressing GIP exhibit increased bone mass and enhanced osteoblast activity at 24 months of age, whilst GIPR KO leads to decreased BMD, cortical thickness, and overall bone strength
Available from: Butler J, Shah SJ, Petrie MC, Borlaug BA, Abildstrm SZ, Davies MJ et al (2024) Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials
This helps reduce swelling by preventing fluid from pooling in the treated areas
[4] If you have a CGM (or even a simple fasting-glucose finger-stick monitor), tracking these markers gives you a vastly clearer picture of whether the medication is working than waiting for the scale to move
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