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We further excluded emergency procedures that took place without fasting, patients with a history of gastroparesis and acute conditions known to cause gastroparesis (such as acute gastrointestinal bleeding and acute pancreatitis), patients with a history of gastric resection, banding or bypass (which are known to be associated with delayed gastric emptying 15 ), and patients who underwent a combined EGD/colonoscopy (because the preprocedural colon preparation regimen has been shown to decrease the incidence of full stomach after fasting 7 )

In summary, an increasing number of clinical studies support that GLP-1 RAs can improve the clinical and pathological changes in PD, providing long-term benefits for patients cognitive and motor symptoms

It is also worth noting that, since the publication of our review, RCTs evaluating subcutaneous semaglutide in psychiatric populations particularly among patients with schizophrenia and those receiving antipsychotic medications have reported findings consistent with ours

But quickly, also, just for actionable takeaways on this Nature Aging paper, things that I was reading, I think maybe the most interesting to me, well, two