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Once reconstituted, immediately refrigerate the vial at 2-8C (36-46F)
After reconstitution, the medication should be administered using the route and rate specified (IV, IM, or SC) per the drugs guidelines
Long-acting amylin analog activating the amylin receptor complex (calcitonin receptor CALCR + receptor activity-modifying proteins RAMP1/2/3) via brainstem area postrema and hypothalamic circuits appetite suppression pathway distinct from GLP-1R
Others stop phentermine first and start semaglutide after a washout period
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