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There are some studies implying that metformin might attenuate weight regain 2
"I've lost about 40 pounds, but it's not just about the weight
In this situation, adipocytes encountering high insulin and low GH levels can only store nutrients and not start lipolysis, the ideal situation for gaining weight instead of losing it
This study showed that use of GLP-1 RAs was not associated with increased incidence of suicide or suicide attempts in either the active comparator new-user design or in the self-controlled case series design
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