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** 1:**
This dual action makes tirzepatide uniquely effective for weight loss
However, glucose scarcity can impair the metabolic fitness and functionality of tumor-infiltrating lymphocytes (TILs) within the TME 764 and diminish the effector function and viability of NK cells, 765 thereby constraining the energy metabolism and antitumor capabilities of these immune cells
And the physical barrier is, is a particle size barrier
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