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Direct provision of TMAO into diet has been shown to increase the development of atherosclerosis in animal models, confirming its pro-atherogenic properties 47 and multiple clinical studies have confirmed that an elevated TMAO level is associated with increased risks for incident major adverse CV events 48

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It is postulated that ADHD may result from deficits in the dopaminergic system in cortical brain structures such as the prefrontal cortex, subcortical areas such as striatum [54, 55]

Brauner S, Ivanchenko M, Thorlacius GE, Ambrosi A, Wahren-Herlenius M