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Another study reported an increased bioavailability of N-3 PUFAs in the frontal cortex after supplementation with fish oil [120, 122]

The decrease in free carnitine availability caused by the increase in carbohydrate flux is a key mechanism for the decrease in the fat oxidation rate [276, 277]

Neither dose showed a statistically significant difference from placebo on the primary outcome of colonic transit time or on any of the secondary outcomes.[7] The strain still has a positive evidence base in the broader literature, but the largest single trial in functional constipation was null