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Documented effects in cell-culture models on fibroblast proliferation rate, collagen Type I synthesis, and matrix metalloproteinase expression
Specifically, DTT was dissolved in DMSO at 250 mM and was added to cultures at final concentrations of 0, 0.5, 1 or 10 mM
When AC was administered alongside a p53-specific inhibitor in human CRC HCT-116 cells, the apoptosis rate was significantly declined
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