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Peptide sequencing is critical for ensuring the quality, safety, and efficacy of GLP-1-based therapeutics: Confirms primary structure integrity Ensures the amino acid sequence matches the intended design Identifies impurities and degradation products Detects unwanted variants formed during synthesis or storage Detects post-translational modifications (PTMs) Helps characterize oxidation, deamidation, and other modifications Ensures biosimilarity and batch consistency Essential for generic development and regulatory approval 2: Why Use LC-MS/MS for GLP-1 Peptide Sequencing

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However, the quality and purity of the sourcing still matter to avoid unnecessary fillers that could irritate the gut

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