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Optimization was performed by comparing the expression levels of fusion proteins and evaluating their agonistic activity towards GLP-1R, antagonistic activity towards GIPR, pharmacokinetic properties, as well as changes in body weight and blood glucose levels
The gutgenital tract microbiota interface and immune crosstalk is a recognised concept in womens health, and diabetes is associated with alterations in vaginal microbiota ecology, particularly around menopause transitions
Goodman, M
The chemistry and biology of inhibitors and pro-drugs targeted to glutathione S-transferases
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