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Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin added to ongoing metformin therapy in patients with type 2 diabetes inadequately controlled with metformin alone

The largest trial of ERAs, SONAR, including 2648 participants with type 2 diabetes and proteinuric CKD, demonstrated that atrasentan on top of RAS inhibition significantly lowered the risk of a doubling of serum creatinine or ESKD compared with placebo by 35% [75]

Retatrutide Side Effects In clinical trials, the most commonly reported side effects were gastrointestinal symptoms, which are similar to those seen with other GLP-1based medications

My former colleagues started teasing me, which was embarrassing