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However, these patients all survived their serious liver injury and fully recovered
Correlating the global signal with the time series of each voxel (Pearsons correlation) yields a whole-brain correlation, which is also considered a weighted form of functional connectivity density [42]
Preclinical studies have examined receptor binding affinity at GIPR and GLP-1R, downstream cAMP signalling, -arrestin recruitment, and metabolic-pathway readouts in cultured cells and rodent tissue
46 Overexpression of efflux transporters such as P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) in tumors limits intracellular drug accumulation, while physical barriers such as the bloodbrain barrier constrain effective delivery to sites such as gliomas
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