Its weight-loss effects are primarily achieved through several mechanisms, including central appetite regulation via hypothalamic pathways enhancing satiety, delayed gastric emptying that prolongs postprandial fullness, improvement of insulin sensitivity and metabolic homeostasis, and reduction of visceral and hepatic fat depots, which may alleviate respiratory mechanical burden and metabolic stress in OSAS (34)
Solihah R, Haris MS
Long-term pharmacovigilance planning, adverse event characterization, real-world evidence generation, and post-marketing surveillance strategies are therefore not secondary considerations, but essential pillars of responsible therapeutic development
Your doctor is in the best position to know important factors that could impact symptoms, including your health history, your GLP-1 dosage, how long youve been taking it, and other medications you are taking, he says